Three synthesis plans for the molecule bipoterpride B were presented during the finals of the 1st Nordic Retrosynthesis Challenge, which could be viewed live on Zoom on May 28th.
The winning team is Robin Peterson and Erik Sundén from Uppsala University with the synthesis plan ”Tralling for Terpenes”.
The jurys motivation:
“The retrosynthetic analysis led to a very elegant proposal for a rather concise (low step count) convergent synthesis of the target molecule. The analysis included high-level computational chemistry to assess the viability of a key step (Diels-Alder cycloaddition). The proposal was also noteworthy for (i) the near absence of protective groups and (ii) good redox economy. The overall presentation was of a very high standard.“
The audience honorary prize goes to Masters in Cleavage, Lund University, Sweden.
The next Nordic Retrosynthesis Challenge will take place in 2027.